1 week ago

Principal Drug Discovery Scientist - Manchester

Manchester Competitive Permanent

Job Reference: 245025

Principal Drug Discovery Scientist – Manchester


A fantastic opportunity has arisen for a Principal Drug Discovery Scientist to join a pioneering drug discovery company based in London. This is an office-based role and there’s great flexibility being offered with 2/3 days a week home-working.


As a Principal Drug Discovery Scientist, you will be responsible for discovering new targets for the companies exciting pipeline. You will work as part of a multi-disciplinary team to establish and manage screening cascades for testing and analysis of compounds from in-vitro and in-vivo studies. This is a strategic role where you will be able to influence strategy to validate new genetic targets.


Responsibilities

  • Work collaboratively with the chemists to define the strategy and screening cascade for internal Drug Discovery projects;
  • Lead experimental design and data interpretation
  • Identify appropriate outsourcing partners
  • Project manage bioscience studies with outsourcing partners, monitoring studies to ensure quality and timely reporting;
  • Interact with scientists in a multidisciplinary setting, including medicinal chemistry, DMPK, structural biology and toxicology
  • Evaluate novel targets to assess level of validation, linkage to disease and feasibility of initiating new drug discovery projects.

 

Experience

  • - Educated to PhD level in a relevant scientific discipline
  • - 5+ years’ experience within the pharma or biotech industry
  • - Experience of defining biology screening cascades for drug discovery targets.
  • - Experience of methodology and data analysis for a broad range of in vitro assays (primary & cellular).
  • - Experience in Oncology or Inflammation disease areas is desirable
  • - Good understanding of the drug discovery process from target identification to candidate selection.
  • - The ability to provide leadership and scientific direction to projects through collaboration and cross-functional interaction.
  • - Experience of collaborating with external partners and / or outsourcing of studies


In return you can expect a competitive package with an attractive share options and bonus scheme. For more information please contact Lauren Gripton at Paramount Recruitment lgripton@pararecruit.com


Keywords- drug discovery, small molecule, target discovery, target validation, pharmaceutical, pharma, biotech, oncology, immunology

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