1 week ago

Principal Scientist Comp Bio - Central Nervous System

Baden-Württemberg Germany 100K - 125K Permanent

Job Reference: PSC/SER_1631199737

Principal Scientist Computational Biology - Central Nervous System!


If you are Scientist specialising in Computational Biology, Central Nervous System and are looking for that next step in your career, then please continue to read this amazing opportunity based in Germany!


You will be part of the Discovery Research area within the Innovation Unit. Through In Silico methods combined with disease biology the client want to increase human disease insights. Their ultimate goal is to drive faster and improved decision making in order to identify impactful first-in-class therapies for their patients.


This position is placed in a multi-disciplinary environment and as a new member of the team you will lead the computational strategy for internal research programs in the "Central Nervous System (CNS) Disease Research" Department.


The CNS department focuses on the development of drugs for psychiatric indications, whereas the global Computational Biology and Digital Sciences department is a key player to achieve this goal and to further disease related new therapeutic concepts from large-scale multi-omics datasets.


Tasks & responsibilities


*In your new role, you work closely with members of CNS Disease Research.

*You drive the computational side of some of the main CNS projects by defining the required work packages and delivering the results on-time and to a high-quality standard.

*You work with multiple-omics data, including transcriptomics (RNAseq, scRNAseq), proteomics, genotyping, and operate automated standard analysis pipelines with Linux-based local HPC and cloud-based environments. That includes working with queuing- and modern pipelining systems.

*With your expertise, you are the interface between CNS Disease Research and the NGS laboratory whilst being responsible for the definition, coordination and implementation of strategies for ongoing projects.

*Furthermore, you undertake extensive data analyses for the generation and testing of hypotheses in the context of new therapeutic concepts in cooperation with other members of the Computational Biology group or scientists from CNS Disease Research.


Requirements


*PhD in bioinformatics, computational biology or systems biology research, alternatively master´s degree in this field with extensive professional experience of working in an international, industrial environment

*Experience in project management, specifically in the definition of project objectives, work packages and timelines as well as in assigning tasks and supervising team members in a matrix organization

*Sound expertise in multiple omics data analysis (e.g. RNA-Seq/single cell RNA-Seq), network biology and advanced data analysis (machine learning modelling, advanced clustering, surrogate variable analysis)

*Understanding of neuroscientific concepts in psychiatric diseases.

*Hands-on experience in analyzing real world and imaging data as well as in signal processing (e.g. EEG data) are a plus

*Expertise in programming with R/Bioconductor (preferred) or Python

*Experience with version control systems (e.g. git/bitbucket) focused on well-documented and reproducible analyses

*Team player with excellent communication skills and innovative thinking


In return the client offers some amazing benefits which include, a bonus, pension, relocation allowance. They also offer a competitive salary, a generous amount of vacation time, and numerous benefits towards your wellness & financial health and work-life balance. Plus, an onsite gym, in-house doctor and best-in-class cafeterias and coffee bars to keep you energised and healthy. The list is endless!



If you wish to hear more about this exciting opportunity then contact Seema Rana on t: +44 (0)121 616 3404 | m: +44 (0)7985 635091 or Email srana@pararecruit.com



Keywords: Data, Pharmaceuticals, Bioinformatics, Biology, Integration, Scientific, Germany, Drug Discovery, Research and development, Product Management, Life Sciences, Scientist, Computational Biology, Central Nervous System, CNS, Omics, Big Data


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